IVIVA Medical was founded with the goal of developing autologous tissue constructs as a solution to end-state renal disease (ESRD). End-stage renal disease affects over 500,000 patients in the United States and despite transplant being the only definitive treatment for ESRD, most will never receive a donor kidney. Our team is leveraging emerging complementary technologies in tissue engineering, 3D additive manufacturing, and stem cell biology in order to realize the potential of regenerative medicine to end donor organ shortage. We are developing bioartificial platforms and systems not only to provide therapies but to serve as the foundational building blocks for the next generation of engineered functionalized tissues.
It is critical that we develop alternative ESRD therapies that will alleviate donor organ demand, reduce mortality, and provide better quality of life for patients. Developing a clinical application that replicates high level native kidney function and physiology requires a scaffold to provide the architecture and stability required for physiologic perfusion and filtration. At IVIVA we’re developing therapies using proprietary printed biologic scaffolds to replicate physiologically functional tissue constructs; platforms with the potential to replicate autologous renal function. Our composite hydrogel scaffolds are created using computer designed architecture and provide a unique starting point for developing many types of perfusable tissue constructs.
Our organ engineering technology is dependent on biomimetic systems capable of replicating physiological conditions in vitro. Along with our tissue engineering platforms we have developed a variety of biomimetic systems capable of modeling whole organ function in a range of tissue types. These systems allow for the modeling of high level tissue function and disease pathology on a whole organ scale, as well as provide a test platform for therapies, devices, and interventions. We have experience developing systems based on both large and small animal models for various organs.
IVIVA Medical is located in Woburn, Massachusetts USA.
66 Cummings Park
Woburn, MA 01801
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